Spiramycin III Price — China Factory EXW 2026

Spiramycin III price Spec: China national standards

China EXW, VAT excluded

Newest China EXW USD 25,176.99 / MT · VAT excluded unchanged as of 20210323

Newest Price 25,176.99

Price Date 20210323

Day's Change 0

Day's Range 25,176.99 - 25,176.99

Month's Change -13,522.12

Month's Range 25,176.99 - 11,654.87

Year's Change +12,601.77

Year's Range 25,176.99 - 12,575.22

Worth flagging the formulation constraint: acetylspiramycin is acid-unstable, so it is typically sold as enteric-coated tablets that must be swallowed whole rather than chewed. Tha...

Opinions

How does spiramycin fit into the macrolide antibiotic supply chain as erythromycin resistance grows?

Worth flagging the formulation constraint: acetylspiramycin is acid-unstable, so it is typically sold as enteric-coated tablets that must be swallowed whole rather than chewed. That processing requirement adds cost and limits which manufacturers can supply finished dosage forms, which in turn shapes how much upstream spiramycin III actually gets pulled through the channel.

Why does spiramycin III matter for pediatric antibiotic formulations?

One caveat for formulators: acetylspiramycin shares cross-resistance with other macrolides, so it is not a universal fallback. Its real value is in palatability and acid stability for pediatric use, not in covering macrolide-resistant strains. Buyers should treat it as a formulation-driven demand stream rather than a resistance-breaking one.

What is driving bulk antibiotic intermediate pricing for macrolides like spiramycin III?

The practical read for buyers is timing. Intermediate prices have already normalized rather than spiking, so there is limited urgency to over-commit on forward contracts. Watch fermentation feedstock costs and any plant maintenance shutdowns instead, since those are the variables most likely to move spiramycin III pricing in the near term.

Spiramycin III price context

What drives Spiramycin III prices

How does spiramycin fit into the macrolide antibiotic supply chain as erythromycin resistance grows?: Worth flagging the formulation constraint: acetylspiramycin is acid-unstable, so it is typically sold as enteric-coated tablets that must be swallowed whole rat...

Why does spiramycin III matter for pediatric antibiotic formulations?: One caveat for formulators: acetylspiramycin shares cross-resistance with other macrolides, so it is not a universal fallback. Its real value is in palatability...

How we assess Spiramycin III price

China factory / mainstream market EXW quotes (VAT excluded where shown) - not a single global public index

Regional and specification detail so buyers can compare like-for-like grades

Landed cost figures from our calculator are planning estimates, not a customs ruling

Overview

Spiramycin III (CAS 24916-52-7, C46H78N2O15, MW 899.12) is a macrolide antibiotic component of the spiramycin complex, produced by Streptomyces species. It appears as a white to off-white powder and functions as a protein synthesis inhibitor targeting the 50S ribosomal subunit.

Pharmaceutical: active against Gram-positive bacteria and certain Gram-negative cocci; used in treating respiratory tract, oral, and soft tissue infections.
Veterinary: applied in livestock and poultry medicine for respiratory and gastrointestinal infections.
Research: serves as a reference standard in antimicrobial susceptibility testing and macrolide mechanism studies.
Intermediate: a precursor in the synthesis of acetylspiramycin and other semisynthetic macrolide derivatives.

China's production landscape centers on fermentation-derived spiramycin complexes, with downstream acetylation yielding acetylspiramycin as a key finished pharmaceutical grade. Domestic output primarily serves the veterinary and pharmaceutical API markets, with limited high-purity reference-standard grades requiring specialized purification. The market remains stable, driven by veterinary demand and research applications.

Key domestic producers:
Hisun Pharmaceutical – spiramycin and acetylspiramycin API manufacturer.
NCPC – veterinary and pharmaceutical macrolide producer.
Luwei Pharmaceutical – fermentation-based macrolide antibiotics.

Properties

Name

Spiramycin III

CAS Number

24916-52-7

HS Code

2941900000

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