Cytosine Price — China Factory EXW 2026

Cytosine price Spec: China national standards

China EXW, VAT excluded

Newest China EXW USD 2,380.53 / MT · VAT excluded unchanged as of 20210320

Newest Price 2,380.53

Price Date 20210320

Day's Change 0

Day's Range 2,380.53 - 2,380.53

Month's Change -141.59

Month's Range 2,380.53 - 2,238.94

Year's Change -16,548.67

Year's Range 2,380.53 - 18,929.2

Keep an eye on feedstock costs—cytosine synthesis often involves malononitrile and urea derivatives, whose prices track upstream petrochemicals. Any spike in those inputs will squ...

Also known as 2-Oxy-4-amino pyrimidine, 4-AMINO-2(1)-PYRIMIDONE, 4-Amino-2(1H)-Pyrimidinone, 4-Amino-2-hydroxypyrimidine

Opinions

What are the supply-side dynamics for cytosine in China's pharmaceutical intermediate market?

Keep an eye on feedstock costs—cytosine synthesis often involves malononitrile and urea derivatives, whose prices track upstream petrochemicals. Any spike in those inputs will squeeze margins for cytosine makers unless they can pass through costs, which is harder when long-term supply contracts are in place.

Why is cytosine a critical upstream material for lamivudine and other antiviral APIs?

Beyond lamivudine, cytosine feeds into 5-fluorocytosine and other nucleoside analogs used in oncology and antivirals. Watch capacity expansions in Henan and Anhui provinces—recent projects show cytosine capacity being added or optimized, which could ease supply tightness and moderate prices in the medium term.

How does cytosine demand correlate with nucleotide metabolism research and nucleic acid drug development?

Also note that cytosine's spontaneous deamination to uracil is a known DNA damage pathway, which has driven research into cytosine analogs as epigenetic tools. This adds a research-grade demand segment beyond pharma, though volumes are smaller compared to antiviral intermediates.

Cytosine price context

What drives Cytosine prices

What are the supply-side dynamics for cytosine in China's pharmaceutical intermediate market?: Keep an eye on feedstock costs—cytosine synthesis often involves malononitrile and urea derivatives, whose prices track upstream petrochemicals. Any spike in t...

Why is cytosine a critical upstream material for lamivudine and other antiviral APIs?: Beyond lamivudine, cytosine feeds into 5-fluorocytosine and other nucleoside analogs used in oncology and antivirals. Watch capacity expansions in Henan and Anh...

How we assess Cytosine price

China factory / mainstream market EXW quotes (VAT excluded where shown) - not a single global public index

Regional and specification detail so buyers can compare like-for-like grades

Landed cost figures from our calculator are planning estimates, not a customs ruling

Overview

Cytosine (4-amino-2-hydroxypyrimidine, CAS 71-30-7) is a white crystalline powder with a melting point above 300°C and good water solubility. It is one of the five primary nucleobases, present in both DNA and RNA, where it pairs with guanine.

Pharmaceutical: a key intermediate for antiviral drugs such as lamivudine and emtricitabine, antitumor agents like gemcitabine and 5-fluorocytosine, and neurological drugs including citicoline.
Biotechnology: a fundamental building block in nucleic acid research, DNA data storage encoding, and nucleotide synthesis.
Agricultural: used in the production of cytidine nucleotides for biological agricultural additives.

China's production landscape centers on chemical synthesis routes, which have largely replaced costly biological extraction methods, enabling large-scale domestic output. The country has become a major supplier of cytosine and downstream nucleoside products, with exports reaching markets in Europe, Japan, and India. Market demand is growing steadily, driven by rising domestic pharmaceutical needs and expanding applications in nucleic-acid-based products.

Key domestic producers:
Tuoxin Pharmaceutical – leading domestic producer of cytosine and nucleoside intermediates.
Xinxiang Huakang Pharmaceutical – operates a 5-fluorocytosine production line.

Properties

Name

Cytosine

2-Oxy-4-amino pyrimidine

4-AMINO-2(1)-PYRIMIDONE

4-Amino-2(1H)-Pyrimidinone

4-Amino-2-hydroxypyrimidine

CAS Number

71-30-7

EINECS No.

200-749-5

Risk Codes

S26;S36;S37/39

Safety Description

R36/37/38;R20/21/22

HS Code

2933591000

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